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KMID : 0354719770040010043
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Journal of Korean Diabetes Association
1977 Volume.4 No. 1 p.43 ~ p.52
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A Clinical Analysis of Rodentcide "RH-787" intoxication in Korea
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李泰熙/Lee, Tai Hee
姜貞埰/韓明童/金鎭束/魯宰源/鄭敏英/Kang, Jung Chai/Han, Myung Dong/Kim, Jin Sohk/Roh, Jae Won/Chung,Min Young
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Abstract
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We studied on 53 R11-787 intoxicated patients prospectively and analyzed 198 reported cases. The results were as follows.
1) The proportion of male to female was 1 to 2.3 ranging from 1 year and 8 months to 67 years of age, and they ingested 5 to 62.5 gm of RH-787 for the suicidal purpose in the majority of patients(66.0/6).
2) Clinical symptoms were nausea (36.80), disturbance of consciousness (36.8%1), abdominal pain, urinary disturbance, sensory disturbance, general weakness, and anorexia.
3) About 80% of patients showed fasting hyperglycemia or abnormal glucose tolerence curve, and :ketosis were in 50% of patients.
4) Such cases as gastric lavages were performed within 15 minutes after ingestion of RH-787 showed no hyperglycemia or abnormal gucose tolernece curve.
5) Abnormal laboratory findings such as leukocytosis(62.5%), elevated BUN and creatinine and prote:inuria, elevated SGOT and alkaline phosphatase levels were noted, they were normalized however, following by control of glucose.
6) Cerebrospinal fluid examination showed normal ranges of pressure, color and, cell counts, but increased glucose (58. 0%) and protein (47. 7,05).
7) Pathologic findings reported as massive necrosis of Langerhan´s island of pancreas, fatty change of liver, vacuoles and acute necrosis in tubular epithelium in kidney.
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KEYWORD
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